Tips on moneyline betting this weekend, Nfl focused

Who do you think stands out as a solid underdog? Any key matchups worth hammering on?
I’ve been eyeing a couple of things:
The Jaguars, they’ve been hot at home, and if their defense shows up, they could surprise.
The Cowboys, risky pick, but I feel they might edge out in a tight one.
Also, are there any big factors, like injuries or weather,I should really watch before placing bets?
 
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